Phaeochromocytoma
A phaeochromocytoma is a rare tumour, usually of the adrenal gland, that produces excess adrenaline and noradrenaline. These hormones can cause sudden, severe episodes of high blood pressure along with other characteristic symptoms. Most are benign, though all require careful diagnosis and management.
Common symptoms
- episodes of high blood pressure, sometimes with normal blood pressure in between
- severe headaches and sweating
- palpitations, tremor, or a racing heart
What we offer
- the correct biochemical blood or urine tests (metanephrines)
- coordinated referral for imaging to locate the tumour
- careful pre-operative preparation and surgical planning where needed
Biochemical testing and imaging
Investigation usually begins with plasma free or urinary fractionated metanephrines under appropriate sampling conditions. Medicines, illness, stress and collection technique can affect results. Imaging follows convincing biochemical evidence unless an urgent clinical situation requires a different pathway.
Treatment and genetic assessment
Confirmed phaeochromocytoma is normally managed by an experienced multidisciplinary team. Careful alpha-blockade and fluid preparation are required before surgery; beta-blockade must not be started first. Genetic assessment may be appropriate because some tumours are hereditary.
UK-wide video consultations
History and result review can often take place securely by video, while biochemical testing, imaging and surgical preparation require local specialist services. Severe headache with chest pain, neurological symptoms or very high blood pressure requires urgent assessment.